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Strain engineering and metabolic flux analysis of a probiotic yeast Saccharomyces cerevisiae for metabolizing L-fucose, a mammalian mucin component

ABSTRACT: Genome scale metabolic model of Saccharomyces cerevisiae that metabolizes L-fucose

SUBMITTER: Jungyeon Kim

PROVIDER: MODEL2209060001 | BioModels | 2025-10-24

REPOSITORIES: BioModels

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Strain engineering and metabolic flux analysis of a probiotic yeast Saccharomyces boulardii for metabolizing L-fucose, a mammalian mucin component.

Kim Jungyeon J Cheong Yu Eun YE Yu Sora S Jin Yong-Su YS Kim Kyoung Heon KH

Microbial cell factories 20221007 1

<h4>Background</h4>Saccharomyces boulardii is a probiotic yeast that exhibits antimicrobial and anti-toxin activities. Although S. boulardii has been clinically used for decades to treat gastrointestinal disorders, several studies have reported weak or no beneficial effects of S. boulardii administration in some cases. These conflicting results of S. boulardii efficacity may be due to nutrient deficiencies in the intestine that make it difficult for S. boulardii to maintain its metabolic activit ...[more]

PMID: 36207743

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