Modeling the relevance of immune and metabolic cues in the macrophage/fibroblast interplay during fibrosis applied to kidney transplantation

ABSTRACT: In this model, we integrate in vitro observations of macrophage/fibroblasts in coculture with hypoxia and inflammatory signals. We obtain conditions under which the wound healing process progresses normally or becomes fibrotic.

SUBMITTER: Josue Nava  

PROVIDER: MODEL2209160001 | BioModels | 2022-09-27

REPOSITORIES: BioModels