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Gall&Pin2022 - ODE model of the intestinal epithelium

ABSTRACT: We developed a compartmental model of the small intestinal epithelium that describes stem and progenitor cell proliferation and differentiation and cell migration onto the villus. The model includes a negative feedback loop from villus cells to regulate crypt proliferation and integrates heterogeneous epithelial-related processes, such as the transcriptional profile, citrulline kinetics and probability of diarrhea.

SUBMITTER: Louis Gall

PROVIDER: MODEL2212120003 | BioModels | 2023-09-04

REPOSITORIES: BioModels

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