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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of C. difficile following environmental stress

ABSTRACT: Data is also available from http://bugs.sgul.ac.uk/E-BUGS-55

INSTRUMENT(S): Anaerobic workstation with airlock

ORGANISM(S): Clostridium difficile

SUBMITTER:

PROVIDER: E-BUGS-55 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress.

Emerson Jenny E JE Stabler Richard A RA Wren Brendan W BW Fairweather Neil F NF

Journal of medical microbiology 20080601 Pt 6

Clostridium difficile is a spore-forming anaerobic bacterium that is an emerging nosocomial threat; incidence of infection in hospitals is increasing, both in frequency and severity, resulting in considerable morbidity and mortality. In order to adapt to the intestinal environment, C. difficile must react to the many stresses involved with colonization, including exposure to antibiotics, which represents the most frequent precipitating agent of C. difficile infection. The responses of C. diffici ...[more]

PMID: 18480334

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