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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization by array of Streptococcus pneumoniae isolates from the Mitis group to identify pneumococcal virulance genes

ABSTRACT: Data is also available from BuG@Sbase

INSTRUMENT(S): NanoDrop

ORGANISM(S): Streptococcus pneumoniae

SUBMITTER:

PROVIDER: E-BUGS-82 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Detection of large numbers of pneumococcal virulence genes in streptococci of the mitis group.

Johnston Calum C Hinds Jason J Smith Andrew A van der Linden Mark M Van Eldere Johan J Mitchell Tim J TJ

Journal of clinical microbiology 20100602 8

Seven streptococcal isolates from the mitis group were analyzed for the presence of pneumococcal gene homologues by comparative genomic hybridization studies with microarrays based on open reading frames from the genomes of Streptococcus pneumoniae TIGR4 and R6. The diversity of pneumolysin (ply) and neuraminidase A (nanA) gene sequences was explored in more detail in a collection of 14 S. pseudopneumoniae and 29 mitis group isolates, respectively. The mitis group isolates used in the microarray ...[more]

PMID: 20519466

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Project description:Data is also available from <ahref=http://bugs.sgul.ac.uk/E-BUGS-84 target=_blank>BuG@Sbase</a>

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