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Transcription profiling by array of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation

ABSTRACT: Data is also available from BuG@Sbase

INSTRUMENT(S): NanoDrop

ORGANISM(S): Staphylococcus aureus

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PROVIDER: E-BUGS-94 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Evolutionary genomics of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation.

Guinane Caitriona M CM Ben Zakour Nouri L NL Tormo-Mas Maria A MA Weinert Lucy A LA Lowder Bethan V BV Cartwright Robyn A RA Smyth Davida S DS Smyth Cyril J CJ Lindsay Jodi A JA Gould Katherine A KA Witney Adam A Hinds Jason J Bollback Jonathan P JP Rambaut Andrew A Penadés José R JR Fitzgerald J Ross JR

Genome biology and evolution 20100712

Phenotypic biotyping has traditionally been used to differentiate bacteria occupying distinct ecological niches such as host species. For example, the capacity of Staphylococcus aureus from sheep to coagulate ruminant plasma, reported over 60 years ago, led to the description of small ruminant and bovine S. aureus ecovars. The great majority of small ruminant isolates are represented by a single, widespread clonal complex (CC133) of S. aureus, but its evolutionary origin and the molecular basis ...[more]

PMID: 20624747

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