Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

13 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcription profiling by array of Helicobacter pylori HP0256 mutants

ABSTRACT: Data is also available from BuG@Sbase

ORGANISM(S): Helicobacter pylori

SUBMITTER:

PROVIDER: E-BUGS-98 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Publications

The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori.

Douillard François P FP Ryan Kieran A KA Lane Michael C MC Caly Delphine L DL Moore Stanley A SA Penn Charles W CW Hinds Jason J O'Toole Paul W PW

BMC microbiology 20100408

<h4>Background</h4>Helicobacter pylori is the causative agent for gastritis, and peptic and duodenal ulcers. The bacterium displays 5-6 polar sheathed flagella that are essential for colonisation and persistence in the gastric mucosa. The biochemistry and genetics of flagellar biogenesis in H. pylori has not been fully elucidated. Bioinformatics analysis suggested that the gene HP0256, annotated as hypothetical, was a FliJ homologue. In Salmonella, FliJ is a chaperone escort protein for FlgN and ...[more]

PMID: 20377912

Similar Datasets

Transcription profiling of Helicobacter pylori bearing FliK mutation to investigate the effect of the mutation on expression of eI?54 sigma factor RpoN in Helicobacter pylori

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-78

2009-04-28 | E-BUGS-78 | biostudies-arrayexpress

Transcription profiling of Helicobacter pyloric wild type and hp0958 knock-out to investigate post-transcriptional regulation of flagellin synthesis by the RpoN chaperone HP0958

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-73

2008-11-13 | E-BUGS-73 | biostudies-arrayexpress

Transcription profiling of S. aureus (MRSA) clones with the same USA300 PFGE profile

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-77

2009-10-12 | E-BUGS-77 | biostudies-arrayexpress

Comparative genomic hybridization of S. aureus to examine Genetic Diversity in CC398 Methicillin-Resistant Staphylococcus aureus of Different Geographic Origin.

Project description:Data is also available from <ahref=http://bugs.sgul.ac.uk/E-BUGS-84 target=_blank>BuG@Sbase</a>

2009-09-22 | E-BUGS-84 | biostudies-arrayexpress

Transcription profiling by array of Staphylococcus aureus reveals insights into the origin and molecular basis of ruminant host adaptation

Project description:Data is also available from <ahref=http://bugs.sgul.ac.uk/E-BUGS-94 target=_blank>BuG@Sbase</a>

2010-08-17 | E-BUGS-94 | biostudies-arrayexpress

Transcription profiling by array of Mycobacterium tuberculosis to analyse the regulatory role of the HigA antitoxin

Project description:Data is also available from <ahref=http://bugs.sgul.ac.uk/E-BUGS-107 target=_blank>BuG@Sbase</a>

2010-07-16 | E-BUGS-107 | biostudies-arrayexpress

Genotyping of Staphylococcus aureus isolates causing gangrenous mastitis versus subclinical mastitis in a dairy sheep flock

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-76

2009-08-07 | E-BUGS-76 | biostudies-arrayexpress

Transcription profiling of S. aureus to investigate an outbreak of severe infections with community-acquired methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin following immunization - duplicate of E-BUGS-45

Project description:BACKGROUND: Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. METHODS AND FINDINGS: We carried out a field investigation after adverse events following immunization (AEFI) were reported. We reviewed the clinical data from all cases. S. aureus recovered from skin infections and from nasal and throat swabs were analyzed by pulse-field gel electrophoresis, multi locus sequence typing, PCR and microarray. In May 2006, nine children presented with AEFI, ranging from fatal toxic shock syndrome, necrotizing soft tissue infection, purulent abscesses, to fever with rash. All had received a vaccination injection in different health centres in one District of Ho Chi Minh City. Eight children had been vaccinated by the same health care worker (HCW). Deficiencies in vaccine quality, storage practices, or preparation and delivery were not found. Infection control practices were insufficient. CA-MRSA was cultured in four children and from nasal and throat swabs from the HCW. Strains from children and HCW were indistinguishable. All carried the Panton-Valentine leukocidine (PVL), the staphylococcal enterotoxin B gene, the gene complex for staphylococcal-cassette-chromosome mec type V, and were sequence type 59. Strain HCM3A is epidemiologically unrelated to a strain of ST59 prevalent in the USA, although they belong to the same lineage. CONCLUSIONS: We describe an outbreak of infections with CA-MRSA in children, transmitted by an asymptomatic colonized HCW during immunization injection. Consistent adherence to injection practice guidelines is needed to prevent CA-MRSA transmission in both in- and outpatient settings. Data is also available from http://bugs.sgul.ac.uk/E-BUGS-45

2009-01-16 | E-BUGS-45 | biostudies-arrayexpress

Transcription profiling of Neisseri meningitidis serogroups and commensal Neisseri

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-29

2007-01-30 | E-BUGS-29 | biostudies-arrayexpress

Comparative genomic hybridization of the dominant strains of Mycobacterium tuberculosis in a UK South Asian community

Project description:Data is also available from http://bugs.sgul.ac.uk/E-BUGS-44

2007-09-06 | E-BUGS-44 | biostudies-arrayexpress