Transcription profiling of pig endothelium from multiple sites of coronary and non-coronary arteries

ABSTRACT: This study investigates the role of endothelial cell (EC) gene expression in the focal origin of atherosclerosis. The EC transcriptome was profiled in multiple arterial regions of normal swine. Specifically, small amounts of EC RNA were isolated from 7 athero-susceptible and 6 athero-protected regions. The number of replicates for each site varied between 4 and 8. A total of 98 samples from 76 animals were used. For each sample, linearly amplified RNA (labeled with Cy5) was co-hybridized with pooled arterial reference RNA (labeled with Cy3) onto a custom-printed porcine oligo microarray (70-mers).

ORGANISM(S): Sus scrofa

SUBMITTER: Peter Davies 

PROVIDER: E-CBIL-42 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress