Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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RNA-Seq of E.tenella Houghton life cycle stages


ABSTRACT: Recent advances in high throughput sequencing methodologies allow the opportunity to probe in depth the transcriptomes of organisms including E. tenella. In this project, we are using Illumina sequencing technology to analyze the transcriptome (RNA-Seq) of experimentally accessible stages (e.g. sporozoites, merozoites, unsporulated oocysts, sporulated oocysts) of E. tenella Houghton. The aim is to make transcriptional landscape maps of different life cycle stages of E. tenella at single base pairs resolution and utilise this information to identify the genes and define the precise gene boundaries. Gene finding has been a rather difficult task in Eimeria. Obtaining the precise transcript boundaries by Illumina RNA-Seq protocol is expected to expedite gene finding in Eimeria tenella. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

ORGANISM(S): Eimeria tenella

SUBMITTER:  

PROVIDER: E-ERAD-109 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genomic analysis of the causative agents of coccidiosis in domestic chickens.

Reid Adam J AJ   Blake Damer P DP   Ansari Hifzur R HR   Billington Karen K   Browne Hilary P HP   Bryant Josephine J   Dunn Matt M   Hung Stacy S SS   Kawahara Fumiya F   Miranda-Saavedra Diego D   Malas Tareq B TB   Mourier Tobias T   Naghra Hardeep H   Nair Mridul M   Otto Thomas D TD   Rawlings Neil D ND   Rivailler Pierre P   Sanchez-Flores Alejandro A   Sanders Mandy M   Subramaniam Chandra C   Tay Yea-Ling YL   Woo Yong Y   Wu Xikun X   Barrell Bart B   Dear Paul H PH   Doerig Christian C   Gruber Arthur A   Ivens Alasdair C AC   Parkinson John J   Rajandream Marie-Adèle MA   Shirley Martin W MW   Wan Kiew-Lian KL   Berriman Matthew M   Tomley Fiona M FM   Pain Arnab A  

Genome research 20140711 10


Global production of chickens has trebled in the past two decades and they are now the most important source of dietary animal protein worldwide. Chickens are subject to many infectious diseases that reduce their performance and productivity. Coccidiosis, caused by apicomplexan protozoa of the genus Eimeria, is one of the most important poultry diseases. Understanding the biology of Eimeria parasites underpins development of new drugs and vaccines needed to improve global food security. We have  ...[more]

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