STUDY THE EFFECT OF TGF beta ON SCHISTOSOME ADULT WORMS

ABSTRACT: STUDY THE EFFECT OF TGF beta ON SCHISTOSOME ADULT WORMSGoal: Primary: Assess the effects of TGF beta on transcription of adult male and female schistosomes. Secondary: Identify the pathways regulated by TGF beta in worm pairs, mature males, mature females, immature males and immature females.METHODS:Parasite: Schistosoma mansoni employed is the NMRI strain that is maintained in a Puerto Rican Biomphalaria glabrata and Golden Syrian hamsters. The life cycle is maintained in the LoVerde lab.Cercariae obtained from infected snails were used to infect experimental animals. The cercariae wre shed from snails exposed to multiple miracidia for mixed infections or from snails exposed to a single miracidia for single-sex infections. Schistosome worms were recovered from hamsters by perfus

INSTRUMENT(S): Illumina Genome Analyzer II

ORGANISM(S): Schistosoma mansoni

SUBMITTER:  

PROVIDER: E-ERAD-190 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress