Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Olfactory transcriptomics in dogs

ABSTRACT: The olfactory gene repertoire is largely species-specific, shaped by the nature and necessityof chemosensory information for survival in each species' niche. We are intrigued by thisinterspecific variation and aim to investigate the olfactory transcriptome across mammals forevidence of selection at the level of receptor gene choice. Having collected this data frommice, rats, cows, and two primates, we now wish to extend the analysis to our final species,the dog.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Canis familiaris

SUBMITTER:

PROVIDER: E-ERAD-420 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Zebrafish olfactory transcriptomics

Project description:High-throughput sequencing of olfactory tissues of adult male zebrafish.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-11-25 | E-ERAD-200 | biostudies-arrayexpress

Single cell transcriptomics in olfactory sensory neurons

Project description:High-throughput sequencing of individual olfactory sensory neurons from adult male mice.A multiplexed library of 72 single cells was prepared and purified using the Nextera XT DNA. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-11-25 | E-ERAD-199 | biostudies-arrayexpress

Transcriptome of the MOE in different mouse strains

Project description:High-throughput RNA sequencing of the main olfactory epithelium in two mouse strains.With this study we aim to dissect the genetic contribution to the expression of the olfactory receptor genes from environmental factors. For this, we housed a single black6 mouse with a 129S5 litter and vice versa, and dissected the MOE of the black6 animal and one 129S5 animal at 10 weeks of age. Three biological replicates were obtained for each combination. RNA was extracted using the Qiagen RNeasy kit using standard protocols. All twelve RNA samples were multiplexed together and sequenced in four lanes on the Illumina HiSeq platform.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2014-04-07 | E-ERAD-231 | biostudies-arrayexpress

Olfactory transcriptomics in a mouse model of Alzheimer s disease

Project description:High-throughput sequencing of RNA from olfactory epithelium of mice modeling Alzheimer's disease with olfactory deficits. We sequenced cDNA libararies from the main olfactory epithelium (MOE) of nine mice from 3 strains (C57BL/6, T43 with P201S mutation, 129S5): 3 groups consists of 9 mice. RNA was extracted using a Qiagen RNAeasy kit and standard methods. All nine RNA samples were multiplexed together and sequenced in three lanes on the Illumina HiSeq platform. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ or email dl5@sanger.ac.uk

2012-07-02 | E-ERAD-160 | biostudies-arrayexpress

Transcriptome of the olfactory system of newborn mice

Project description:High-throughput RNA sequencing of the olfactory system of newborn mice.With this study we aim to assess the expression profile of the main olfactory epithelium (MOE) and the vomeronasal organ (VNO) at birth in C57BL/6J mice. Tissue was collected from P0.5 pups and three to four individuals were pooled for each sample. Three biological replicates were obtained for each organ. RNA was extracted using the Qiagen RNeasy kit using standard protocols. All six RNA samples were multiplexed together and sequenced in two lanes on the Illumina HiSeq platform.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-08-07 | E-ERAD-169 | biostudies-arrayexpress

Rat olfactory transcriptome

Project description:High-throughput sequencing on the Illumina platform of olfactory and vomeronasal tissues of adult male rats.This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-08-27 | E-ERAD-182 | biostudies-arrayexpress

Cestode transcriptomics

Project description:The main objective of this project is to recognize genes expressed in the life stages and tissue types of a variety of different cestode species, including Echinococcus multilocularis, E. granulosus, Hymenolepis microstoma, H. nana and others. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-02-28 | E-ERAD-50 | biostudies-arrayexpress

Transcriptional response of the mouse intestinal mucosa to infection by the parasitic nematode Trichuris muris

Project description:This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ The human-infective whipworm Trichuris trichiura is estimated to infect up to a billion people and is responsible for considerable morbidity, especially in children of developing countries. The closely related species T. muris is a naturally occurring nematode parasite of mice that serves as a remarkably tractable model system for dissecting immune responses and host-parasite relationships. Such studies are of relevance beyond parasitology as helminths have arguably had a significant impact on the evolution of the mammalian immune system. Both Trichuris species reside in the caecum and colon of the host where they burrow their front end for feeding into the intestinal mucosa, thereby breaching the mucus barrier and allowing access of the microflora directly to the epithelium. The interplay of intestinal helminths, the bacterial microflora and the host immune system is currently a research focus in various laboratories (Bancroft et al 2012). This study will study the transcriptional responses of the intestinal mucosa (caecum) from infected and uninfected mice.

2013-05-07 | E-ERAD-181 | biostudies-arrayexpress

Variation in gene transcription between life stages of Trypanosoma vivax

Project description:Trypanosoma vivax is a major pathogen of domestic cattle and wildlife across sub-Saharan Africa. For many years, the WTSI has had a research interest in developing a genome sequence for T. vivax, as part of a wider programme concerning African trypanosome parasites of Humans and animals. In 2012 a draft genome sequence for T. vivax Y486 was published by the WTSI and our collaborators in comparison with related species, T. brucei and T. congolense. This study identified numerous putative genes in T. vivax that have no known affinity and are therefore species-specific. A related transcriptomic study confirmed that some of these putative genes are transcribed, but lacked accuracy and was based on a single parasite life stage only. Until recently, it has not been possible to culture different T. vivax life stages in refined media. There is now the opportunity to use new approaches to produce whole cell RNA for both insect and bloodstream parasite stages. We sequence stage-specific cDNA and identify stage-specific genes, and compare these features with similar data already available for T. brucei and T. congolense, which display substantial differences in their developmental cycles. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

2013-03-07 | E-ERAD-100 | biostudies-arrayexpress

S mansoni male and female adult worm reproductive organs pre and post pairing

Project description:Study description:This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ Schistosomes are blood dwelling digenean trematodes that mature as adults in the intestinal or urinary veins, predominantly of mammals. Adult female Schistosomes produce eggs of which approximately 40% fail to pass into faeces or urine (species-dependent) but are dispersed by the blood stream into different organs where they provoke severe inflammation. This parasitic infection is known as schistosomiasis and considered by the WHO as the second most socioeconomically devastating parasitic disease, next only to malaria, with hundreds of millions infected worldwide. As the eggs represent the causative pathogenic agents, the understanding of egg forming processes, and therefore of the schistosomal reproductive biology in general, is of fundamental interest. Additionally the differences between immature (pre-mating) and mature (post-mating) adult worms are of significant interest; adults only reach maturity upon mating. Trasncriptomic sequencing of gonad-specific cellular material will help to unravel signal transduction cascades involved in e.g. gametogenesis and/or vitellogenesis. This project aims to characterize the transcriptome profiles of immature and mature adult ovaries and adult testes.

2016-07-05 | E-ERAD-516 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data