Transcription profiling of human MCF7 cells following short-term E deprivation, ER-alpha siRNA knockdown and oxidant treatments

ABSTRACT: To investigate the oxidant sensitivity of E/ER regulated gene expression, E/ER regulated genes are identified using E deprivation or; ER-alpha siRNA knockdown; and oxidative stress responsive is determined by 8hr exposure to diamide, hydrogen peroxide and menadione Experiment Overall Design: MCF7 cells were treated under various conditions to identifiy oxidative stress responsive E/ER regulated genes. Association of these genes with respect to tumor phenotypes are assessed

ORGANISM(S): Homo sapiens

SUBMITTER: Christina Yau 

PROVIDER: E-GEOD-10061 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress