Molecular profiles(HG-U95B,C,D,E) of dystrophin-deficient and normal human skeletal muscle
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Judith Haslett
PROVIDER: E-GEOD-1007 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Gene expression profiling of Duchenne muscular dystrophy skeletal muscle.
Haslett Judith N JN Sanoudou Despina D Kho Alvin T AT Han Mei M Bennett Richard R RR Kohane Isaac S IS Beggs Alan H AH Kunkel Louis M LM
Neurogenetics 20030416 4
The primary cause of Duchenne muscular dystrophy (DMD) is a mutation in the dystrophin gene, leading to absence of the corresponding protein, disruption of the dystrophin-associated protein complex, and substantial changes in skeletal muscle pathology. Although the primary defect is known and the histological pathology well documented, the underlying molecular pathways remain in question. To clarify these pathways, we used expression microarrays to compare individual gene expression profiles for ...[more]
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