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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Wounded versus nonwounded drosophila embryos

ABSTRACT: Elucidation of the wound response genes in Drosophila embryos Keywords: response to wounding wild-type drosophila embryos were wounded by laser ablation and compared to unwounded embryos.

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Mark Winfield

PROVIDER: E-GEOD-10207 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos.

Stramer Brian B Winfield Mark M Shaw Tanya T Millard Thomas H TH Woolner Sarah S Martin Paul P

EMBO reports 20080314 5

By using a microarray screen to compare gene responses after sterile laser wounding of wild-type and 'macrophageless' serpent mutant Drosophila embryos, we show the wound-induced programmes that are independent of a pathogenic response and distinguish which of the genes are macrophage dependent. The evolutionarily conserved nature of this response is highlighted by our finding that one such new inflammation-associated gene, growth arrest and DNA damage-inducible gene 45 (GADD45), is upregulated ...[more]

PMID: 18344972

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Expression study of 'hemocyte minus vs hemocyte plus, and wounded vs unwounded hemocyte deficient' drosophila embryos

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2010-05-22 | E-GEOD-10225 | biostudies-arrayexpress

wounded vs unwounded hemocyte deficient embryos

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hemocyte minus versus hemocyte plus drosophila embryos

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HOXA3 expression in wound tissue

Project description:To investigate how HOXA3 expression in wound tissue alters gene expression to control selective recruitment of bone marrow-derived cell populations, we utilized murine whole genome expression arrays (MEEBO arrays) to identify differentially expressed genes in cutaneous wounds from db/db (diabetic) mice treated with either CMV-HOXA3 or control plasmid. In addition to unwounded control skin, we chose day 4 as the time point to harvest the wounds for RNA isolation, which represents the transition from inflammatory to proliferative phase of wound repair, and precedes the observed differences in BMDC mobilization and recruitment at day 7. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Disease State: cutaneous wound/control skin unwounded skin, wounded skin treated with control plasmid, wounded skin treated with HOXA3

2009-10-12 | E-GEOD-13324 | biostudies-arrayexpress

Embryo study

Project description:knock-out of Gtf2iRD1 or TFII-I in embryos 2 biological replicates of Gtf2iRD1 knockout vs wild type embryos 2 biological replicates of TFII-I knockout vs wild type embryos

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Serine protease-mediated wounding identifies localized epidermal wound response genes in Drosophila melanogaster

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2013-08-12 | E-MEXP-3755 | biostudies-arrayexpress

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