Transcription profiling of maize segmental aneuploid to study phenotypic and gene expression changes associated with aneuploidy

ABSTRACT: ABSTRACT: BACKGROUND: While changes in chromosome number that result in aneuploidy are associated with phenotypic consequences such as Down syndrome and cancer, the molecular causes of specific phenotypes and genome-wide expression changes that occur in aneuploids are still being elucidated. RESULTS: We employed a segmental aneuploid condition in maize to study phenotypic and gene expression changes associated with aneuploidy. Maize plants that are trisomic for 90% of the short arm of chromosome 5 and monosomic for a small distal portion of the short arm of chromosome 6 exhibited a phenotypic syndrome that includes reduced stature, tassel morphology changes and the presence of knots on the leaves. The knotted-like homeobox gene knox10, which is located on the short arm of chromosome 5, was

ORGANISM(S): Zea mays

SUBMITTER: Nathan Springer 

PROVIDER: E-GEOD-10243 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress