Transcription profiling of human lymphoblastoid cell lines that are part of the NIHPDR exposed to N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) to identify novel predictors of resistance to DNA damaging agents

ABSTRACT: We have investigated whether gene expression signatures can be used to predict inter-individual responses to DNA damaging agents; We used microarrays to detail inter-individual variation in gene expression across a healthy population under basal and damage induced conditions Experiment Overall Design: lymphoblastoid cell lines that are part of the NIHPDR were examine for gene expression differences as well as killing upon exposure to MNNG

ORGANISM(S): Homo sapiens

SUBMITTER: Rebecca Fry 

PROVIDER: E-GEOD-10313 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress