Transcription profiling of human synovial macrophages from rheumatoid arthritis patients

ABSTRACT: Macrophages from RA synovial fluids were compared to primary human blood-derived macrophages. Experiment Overall Design: Macrophages from synovial fluids of five RA patients were isolated by ficoll density gradient centrifugation, followed by positive selection of CD14+ cells using magnetic beads. The patientsâ?? diagnoses were determined by their physicians, in each case a Board-certified rheumatologist at the Hospital for Special Surgery, and were definite RA according to American College of Rheumatology criteria. De-identified samples were processed in an anonymous manner using a protocol approved by the Institutional Review Board of the Hospital for Special Surgery. Experiment Overall Design: Human peripheral blood mononuclear cells were isolated from venous blood of independent healt

ORGANISM(S): Homo sapiens

SUBMITTER: Taras Antoniv 

PROVIDER: E-GEOD-10500 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress