Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparison between Estrogen receptor positive and Estrogen receptor negative breast cancer samples


ABSTRACT: Comparison between Estrogen receptor positive and Estrogen receptor negative breast cancer samples Keywords: breast cancer type comparison 152 unique breast cancer tissue sample are included in the analysis. The total mRNA has been labeled with Cy5 and then hybridized on a two color arrays against the stratagen Human common reference that was previously labelled with Cy3.

ORGANISM(S): Homo sapiens

SUBMITTER: Alberto Calabro 

PROVIDER: E-GEOD-10510 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer.

Calabrò Alberto A   Beissbarth Tim T   Kuner Ruprecht R   Stojanov Michael M   Benner Axel A   Asslaber Martin M   Ploner Ferdinand F   Zatloukal Kurt K   Samonigg Hellmut H   Poustka Annemarie A   Sültmann Holger H  

Breast cancer research and treatment 20080701 1


The involvement of the immune system for the course of breast cancer, as evidenced by varying degrees of lymphocyte infiltration (LI) into the tumor is still poorly understood. The aim of this study was to evaluate the prognostic value of LI in breast cancer samples using microarray-based screening for LI-associated genes. Starting from the observation that most published ER gene signatures are heavily influenced by the LI effect, we developed and applied a novel approach to dissect molecular si  ...[more]

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