Specific, Durable and Accurate Gene Expression Signatures of Radiation Response in Mice and Humans

ABSTRACT: Previous work has demonstrated the potential for peripheral blood (PB) gene expression profiling for the detection of disease or environmental exposures. We have sought to determine the impact of several variables on the PB gene expression profile of an environmental exposure, ionizing radiation, and to determine the specificity of the PB signature of radiation versus other genotoxic stresses. Keywords: peripheral blood, gene expression study, radiation reponse We have sought to determine the impact of several variables on the PB gene expression profile of an environmental exposure, ionizing radiation, and to determine the specificity of the PB signature of radiation versus other genotoxic stresses. Neither genotype differences nor the time of PB sampling caused any lessening of the ac

ORGANISM(S): Mus musculus

SUBMITTER: Holly Dressman 

PROVIDER: E-GEOD-10640 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress