A New Class of Homoserine Lactone Quorum Sensing Signals

ABSTRACT: Quorum sensing is a term used to describe cell-to-cell communication that allows cell density-dependent gene expression. Many Gram-negative bacteria use acyl-homoserine lactone (acyl-HSL) synthases to generate fatty acyl-HSL quorum sensing signals, which function with signal receptors to control expression of specific genes. The fatty acyl group is derived from fatty acid biosynthesis and provides signal specificity, but the variety of signals is limited. We have discovered that the photosynthetic bacterium Rhodopseudomonas palustris uses an acyl-HSL synthase to produce p-coumaroyl-HSL by using environmental p-coumaric acid rather than fatty acids from cellular pools. The bacterium has a signal receptor with homology to fatty acyl-HSL receptors that responds to p-coumaroyl-HSL to regulate

ORGANISM(S): Rhodopseudomonas palustris CGA009

SUBMITTER: Gili Bittan-Banin 

PROVIDER: E-GEOD-10642 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress