The effects of artificial tethering of chromosomes to the nuclear periphery using LacI/lap2b anchorage constructs

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE10697: Self-Self Hybridisation were used to set confidence 99% intervals GSE10698: The effects of artificial tethering of chromosomes to the nuclear periphery using LacI/lap2b anchorage constructs 1 GSE10699: The effects of artificial tethering of chromosomes to the nuclear periphery using LacI/lap2b anchorage constructs 2 Background: The spatial organisation of the genome in the nucleus has a role in the regulation of gene expression. In mammals, chromosomal regions with low gene-density are located close to the nuclear periphery. Correlations have also been made between the transcriptional state of some genes and their location near the nuclear periphery. However, a crucial issue is whether this level of nuclear organisatio

ORGANISM(S): Homo sapiens

SUBMITTER: Lee Finlan 

PROVIDER: E-GEOD-10701 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress