Transcription profiling by array of mouse tissues from different mouse strains to investigate the effects of copy number variation on gene expression

ABSTRACT: Copy number variation (CNV) of DNA segments has recently been identified as a major source of genetic diversity, but a more comprehensive understanding of the extent and phenotypic effect of this type of variation is only beginning to emerge. In this study we generated genome-wide expression data from 6 mouse tissues to investigate how CNVs influence gene expression. Keywords: genetic background, gene expression profiling C57BL/6J, DBA2/J, AKR/J, A/J and C3HeB/FeJ were purchased from The Jackson Laboratory and 129S2 from Charles River, France. Six tissues were dissected from three males of 11-14 weeks of age, for each strain.

ORGANISM(S): Mus musculus

SUBMITTER: Charlotte Henrichsen 

PROVIDER: E-GEOD-10744 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress