SiRNA knockdown of NatB N-terminal acetyltransferase (hNAT5) expression in human Hela cells with specific siRNAs

ABSTRACT: Search for genes differently expressed when we inhibit NatB N-terminal acetyltransferase. We compare gene expression after inhibiting hNAT5 expression in Hela cells with specific siRNAs expressed with adenoviruses. Experiment Overall Design: We analyzed duplicate samples and we used as controls Hela cells and Hela cells that express a siRNA that doesn't inhibit any gene expression. Experiment Overall Design: The N-terminal acetyltransferase NatB, composed in Saccharomyces cerevisiae by the Nat3p and Mdm20p subunits, is an important factor for yeast growth and resistance to several stress agents. However, the expression and functional role of the mammalian counterpart has not yet been analysed. Here, we report the identification of Nat3p human homologue (hNAT5/hNAT3) and the characterizatio

ORGANISM(S): Homo sapiens

SUBMITTER: Rafael Aldabe 

PROVIDER: E-GEOD-10779 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress