Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Tumor biopsies from 71 untreated patients with mantle cell lymphoma

ABSTRACT: The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma Keywords: lymphochip; MCL; untreated Tumor biopsies from 71 untreated patients with mantle cell lymphoma

ORGANISM(S): Homo sapiens

SUBMITTER: Thomas Dandekar

PROVIDER: E-GEOD-10793 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis.

Blenk Steffen S Engelmann Julia C JC Pinkert Stefan S Weniger Markus M Schultz Jörg J Rosenwald Andreas A Müller-Hermelink Hans K HK Müller Tobias T Dandekar Thomas T

BMC cancer 20080416

<h4>Background</h4>Mantle cell lymphoma (MCL) is an incurable B cell lymphoma and accounts for 6% of all non-Hodgkin's lymphomas. On the genetic level, MCL is characterized by the hallmark translocation t(11;14) that is present in most cases with few exceptions. Both gene expression and comparative genomic hybridization (CGH) data vary considerably between patients with implications for their prognosis.<h4>Methods</h4>We compare patients over and below the median of survival. Exploratory princip ...[more]

PMID: 18416826

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Dataset Information

Tumor biopsies from 71 untreated patients with mantle cell lymphoma

Publications

Explorative data analysis of MCL reveals gene expression networks implicated in survival and prognosis supported by explorative CGH analysis.

Similar Datasets

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