Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

T-cell lymphoblastic lymphomas induced by gamma-irradiation

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE10858: Comparative Genomic hybridization of gamma-irradiated T-cell lymphomas GSE10859: Expression patterns of cDNAs in gamma-irradiation induced T-cell lymphomas GSE10891: Gamma-irradiation induced T-cell lymphomas (miRNA study) Keywords: SuperSeries Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Marcos Malumbres 

PROVIDER: E-GEOD-10861 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

Bueno María J MJ   Pérez de Castro Ignacio I   Gómez de Cedrón Marta M   Santos Javier J   Calin George A GA   Cigudosa Juan C JC   Croce Carlo M CM   Fernández-Piqueras José J   Malumbres Marcos M  

Cancer cell 20080601 6

The mammalian genome contains several hundred microRNAs that regulate gene expression through modulation of target mRNAs. Here, we report a fragile chromosomal region lost in specific hematopoietic malignancies. This 7 Mb region encodes about 12% of all genomic microRNAs, including miR-203. This microRNA is additionally hypermethylated in several hematopoietic tumors, including chronic myelogenous leukemias and some acute lymphoblastic leukemias. A putative miR-203 target, ABL1, is specifically  ...[more]

Similar Datasets

Transcriptomics Gamma-irradiation induced T-cell lymphomas (miRNA study)
2010-05-26 | E-GEOD-10891 | biostudies-arrayexpress
Transcriptomics Expression patterns of cDNAs in gamma-irradiation induced T-cell lymphomas
2010-05-26 | E-GEOD-10859 | biostudies-arrayexpress
Transcriptomics Comparative Genomic hybridization of gamma-irradiated T-cell lymphomas
2010-05-26 | E-GEOD-10858 | biostudies-arrayexpress
Transcriptomics microRNA expression profile of activated versus non activated primary B cells
2008-08-20 | E-GEOD-12176 | biostudies-arrayexpress
Transcriptomics microRNA expression profile of activated primary B cells and miR181b overexpressing primary B cells
2008-08-20 | E-GEOD-12186 | biostudies-arrayexpress
Genomics Comparative Genomic hybridization of gamma-irradiated T-cell lymphomas
2008-06-26 | GSE10858 | GEO
Genomics,Multiomics
| PRJNA107361 | ENA
Genomics,Multiomics Mus musculus
| PRJNA108893 | ENA
Transcriptomics Expression patterns of cDNAs in gamma-irradiation induced T-cell lymphomas
2008-06-26 | GSE10859 | GEO
Genomics Gamma-irradiation induced T-cell lymphomas (miRNA study)
2008-06-26 | GSE10891 | GEO