Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcription profiling of mouse with abalated dopaminoceptive neurons to examine the effects of CaMKIV loss on cocaine-induced gene expression in the striatum


ABSTRACT: Ablation of the Camk4 gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed from a BAC-derived Drd1a promoter. Our goal was to analyze how loss of CaMKIV will affect acitivity-regulated transcription induced by strong stimulation, i.e. cocaine. Experiment Overall Design: Animals were injected i.p. with either 25 mg/kg cocaine or saline and sacrificed after one hour by cervical dislocation. Expression profiling was performed using total RNA isolated from the striatum.

ORGANISM(S): Mus musculus

SUBMITTER: Jan Rodriguez Parkitna 

PROVIDER: E-GEOD-10869 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2010-03-04 | E-GEOD-10870 | biostudies-arrayexpress
2008-09-10 | GSE10869 | GEO
2013-01-10 | E-GEOD-43410 | biostudies-arrayexpress
2010-01-21 | E-GEOD-18055 | biostudies-arrayexpress
2009-04-30 | GSE10870 | GEO
2014-07-22 | PXD000990 | Pride
2011-05-13 | E-GEOD-29261 | biostudies-arrayexpress
2015-02-27 | E-GEOD-66347 | biostudies-arrayexpress
2015-02-27 | E-GEOD-66349 | biostudies-arrayexpress
2015-02-23 | E-GEOD-63748 | biostudies-arrayexpress