Transcription profiling of mouse lung from E18, P1, P4, P7, P10, P14, P21, and adult) or pooled (E12, E14, E16) - developmental series

ABSTRACT: Mammalian lung development is a complex morphogenetic process, which initiates near mid-gestation and continues through early postnatal life. The lung arises as two lateral buds that emerge from the ventral foregut endoderm at ~ 9 days after fertilization (in mouse) and undergo numerous rounds of dichotomous branching to form the bronchial tree. This stage of development is referred to as the pseudoglandular phase, histologically characterized by loose mesenchyme surrounding undifferentiated epithelial tubes. We have undertaken a comprehensive gene expression profiling of the entire process of murine lung development using oligonucleotide-based microarrays. Our data reveals the expression pattern of ~ 11,000 genes throughout the morphologic stages of lung development. Examination of the da

ORGANISM(S): Mus musculus

SUBMITTER: Soumyaroop Bhattacharya 

PROVIDER: E-GEOD-10889 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress