Differential gene expression analysis for S.pyogenes SP-STK(-) mutant

ABSTRACT: This analysis revealed ~17.% of all ORFs (292 out of a total 1697 ORFs) differed by at least 1.5 fold (Log2 +0.6) between the mutant and wild-type strains. Of these, ~45% of the ORFs (130 out of 292 ORFs) revealed at least 2-fold (Log2 +1) differences. The complete spectrum of differentially expressed genes in the muatnt strain revealed almost equal number of genes up (143, 49%) or down-regulated (149, 51%). However, at a higher stringency (at least 2-fold), this distribution revealed slightly more leaning towards down-regulated genes (74 out of 130, 57%) indicating the lack of SP-STK results into down regulation of several genes. Amongst the genes belonging to different functional categories, the most notable genes that were affected by the absence of SP-STK were those correspond to

ORGANISM(S): Streptococcus pyogenes

SUBMITTER: Vijay Pancholi 

PROVIDER: E-GEOD-10914 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress