Confirmation of the gene expression pattern in Mxi1-deficient mouse (time course)

ABSTRACT: For final aim to completes network map between gene that is concerned in cystogenesis, verifies meaning genes connected with cyst formation analyzing gene pattern in time-dependent Mxi1 KO mouse that have phenotype of polycystic kidney disease. Monitoring meaning genes through microarray analysis, and confirm the function of these genes. Also, find pathway including meaning genes and new pathway related with PKD. Completes network map concerned in time-dependent cystogenesis through integrates knowing pathway and predicting pathway. Develope diagnostic of cyst disease and cure target through such completed network map, and wish to clear new role of cyst formation connection gene through in vivo model and examine closely control system of cyst formation mechanism. Keywords: time course Use 1 mouse at each time experiment and control(total 12 mice). Indirect labeling of 10g cRNA, using bacterial control mRNA.

ORGANISM(S): Mus musculus

SUBMITTER: Min Joo Lee 

PROVIDER: E-GEOD-10941 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress