Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

ABSTRACT: Using transcriptomics, the strain-specific metabolism was mapped for two whole-genome sequenced strains of Aspergillus niger Keywords: Strain comparison Two strains grown in controlled bioreactors, three biological replicates each.

ORGANISM(S): Aspergillus niger

SUBMITTER: Mikael Andersen 

PROVIDER: E-GEOD-10983 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88.

Andersen Mikael R MR   Salazar Margarita P MP   Schaap Peter J PJ   van de Vondervoort Peter J I PJ   Culley David D   Thykaer Jette J   Frisvad Jens C JC   Nielsen Kristian F KF   Albang Richard R   Albermann Kaj K   Berka Randy M RM   Braus Gerhard H GH   Braus-Stromeyer Susanna A SA   Corrochano Luis M LM   Dai Ziyu Z   van Dijck Piet W M PW   Hofmann Gerald G   Lasure Linda L LL   Magnuson Jon K JK   Menke Hildegard H   Meijer Martin M   Meijer Susan L SL   Nielsen Jakob B JB   Nielsen Michael L ML   van Ooyen Albert J J AJ   Pel Herman J HJ   Poulsen Lars L   Samson Rob A RA   Stam Hein H   Tsang Adrian A   van den Brink Johannes M JM   Atkins Alex A   Aerts Andrea A   Shapiro Harris H   Pangilinan Jasmyn J   Salamov Asaf A   Lou Yigong Y   Lindquist Erika E   Lucas Susan S   Grimwood Jane J   Grigoriev Igor V IV   Kubicek Christian P CP   Martinez Diego D   van Peij Noël N M E NN   Roubos Johannes A JA   Nielsen Jens J   Baker Scott E SE  

Genome research 20110504 6

The filamentous fungus Aspergillus niger exhibits great diversity in its phenotype. It is found globally, both as marine and terrestrial strains, produces both organic acids and hydrolytic enzymes in high amounts, and some isolates exhibit pathogenicity. Although the genome of an industrial enzyme-producing A. niger strain (CBS 513.88) has already been sequenced, the versatility and diversity of this species compel additional exploration. We therefore undertook whole-genome sequencing of the aci  ...[more]

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