Detection of virulence and antibiotic resistance gene families

ABSTRACT: Emerging known and unknown pathogens create profound threats to public health. Platforms for rapid detection and characterization of microbial agents are critically needed to prevent and respond to disease outbreaks. Available detection technologies cannot provide broad functional information about known and novel organisms. As a step toward developing such a system, we have produced and tested a series of high-density functional gene arrays to detect elements of virulence and antibiotic resistance mechanisms. Our first generation array targets genes from Escherichia coli strains K12 and CFT073, Enterococcus faecalis and Staphylococcus aureus. We determined optimal probe design parameters for gene family detection and discrimination. When tested with organisms at varying phylogenetic dista

ORGANISM(S): Staphylococcus aureus subsp. aureus Mu50

SUBMITTER: Crystal Jaing 

PROVIDER: E-GEOD-11010 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress