Gene expression induced in Escherichia coli O157:H7 upon exposure to model apple juice

ABSTRACT: Escherichia coli O157:H7 has caused serious outbreaks of foodborne illness via transmission in a variety of food vehicles, including unpasteurized apple juice, dried salami, and spinach. To understand how this pathogen responds to the multiple stresses of the food environment, we compared global transcription patterns after exposure to apple juice. Transcriptomes of mid-exponential and stationary phase cells were evaluated after 10 minutes in model apple juice (pH3.5) using microarrays probing 4,886 ORFs. Significant changes in gene expression were determined using R/MAANOVA and the Fs test. A total of 331 ORFs were significantly induced upon exposure of cells to model apple juice and included genes involved in the acid and osmotic stress responses as well as the oxidative stress respon

ORGANISM(S): Escherichia coli

SUBMITTER: Sivapriya Kailasan Vanaja 

PROVIDER: E-GEOD-11052 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress