Transcription profiling of mouse blastocyst after embryo biopsy

ABSTRACT: Preimplantation Genetic Testing (PGT), which encompasses both Preimplantation Genetic Diagnosis (PGD) and Preimplantation Genetic Screening (PGS), is a form of prenatal screening done on embryos conceived through assisted reproduction techniques (ART) prior to the initiation of pregnancy to ensure that only select embryos are used for transfer. PGT is typically performed on 8-cell embryos derived from either in vitro fertilization or intracytoplasmic sperm injection (ICSI) followed by extended culture. PGT requires a highly invasive embryo biopsy procedure that involves 1) incubating embryos in divalent-cation-deficient medium to disrupt cell adhesion, 2) breaching the protective zona pellucida with acid Tyrode’s, laser drilling, or mechanical force and 3) aspirating one or two blastom

ORGANISM(S): Mus musculus

SUBMITTER: Francesca Elizabeth Duncan 

PROVIDER: E-GEOD-11206 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress