Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of mouse developing placenta


ABSTRACT: This SuperSeries is composed of the following subset Series:; GSE11220: Timecourse of developing mouse placenta, with placental and decidual tissues profiled separately; GSE11222: Placental and decidual timecourse samples normalized and modeled with an undissected e17 sample Experiment Overall Design: Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Kirstin Knox 

PROVIDER: E-GEOD-11224 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genomic evolution of the placenta using co-option and duplication and divergence.

Knox Kirstin K   Baker Julie C JC  

Genome research 20080313 5


The invention of the placenta facilitated the evolution of mammals. How the placenta evolved from the simple structure observed in birds and reptiles into the complex organ that sustains human life is one of the great mysteries of evolution. By using a timecourse microarray analysis including the entire lifetime of the placenta, we uncover molecular and genomic changes that underlie placentation and find that two distinct evolutionary mechanisms were utilized during placental evolution in mice a  ...[more]

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