Lifestyle of lactobacillus plantarum in the mouse cecum

ABSTRACT: Lactobacillus plantarum is a common inhabitant of mammalian gastrointestinal tracts and specific strains belonging to this species are marketed as probiotics intended to confer beneficial health effects. To assist in determining the physiological status and host-microbe interactions of L. plantarum in the digestive tract we assessed changes in the transcriptome of L. plantarum WCFS1 during colonization of the cecum of germ-free mice. According to the transcript profiles L. plantarum WCFS1 was metabolically active and not under severe stress in this intestinal compartment. Carbohydrate metabolism was the most strongly affected functional gene category whereby many genes encoding diverse sugar transport and degradation pathways were induced in mice even compared to L. plantarum grown in a mo

ORGANISM(S): Lactobacillus plantarum WCFS1

SUBMITTER: Douwe Molenaar 

PROVIDER: E-GEOD-11383 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress