Transcript Analysis of Human Mammary Cell Subsets
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: BCGSC BC Cancer Agency
PROVIDER: E-GEOD-11395 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Transcriptome analysis of the normal human mammary cell commitment and differentiation process.
Raouf Afshin A Zhao Yun Y To Karen K Stingl John J Delaney Allen A Barbara Mary M Iscove Norman N Jones Steven S McKinney Steven S Emerman Joanne J Aparicio Samuel S Marra Marco M Eaves Connie C
Cell stem cell 20080701 1
Mature mammary epithelial cells are generated from undifferentiated precursors through a hierarchical process, but the molecular mechanisms involved, particularly in the human mammary gland, are poorly understood. To address this issue, we isolated highly purified subpopulations of primitive bipotent and committed luminal progenitor cells as well as mature luminal and myoepithelial cells from normal human mammary tissue and compared their transcriptomes obtained using three different methods. El ...[more]
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