Expression QTL mapping of Toxoplasma gondii genes, Tachyzoite array

ABSTRACT: Toxoplasma gondii is an intracellular parasite with a significant impact on human health, especially in cases where individuals are immunocompromised (e.g., due to HIV/AIDS). In Europe and North America only a few clonal genotypes appear to be responsible for the vast majority of Toxoplasma infections, and these clonotypes have been intensely studied to identify strain-specific phenotypes that may play a role in the manifestation of more severe disease. To identify and genetically map strain-specific differences in gene expression, we have carried out expression quantitative trait locus (eQTL) analysis on Toxoplasma gene expression phenotypes using spotted cDNA microarrays. This led to the identification of 16 Toxoplasma genes that had significant and mappable strain-specific variation

ORGANISM(S): Toxoplasma gondii

SUBMITTER: Jon Boyle 

PROVIDER: E-GEOD-11514 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress