FAIRE-chip in MCF7 and LNCaP

ABSTRACT: The compaction degree of chromatin is intimately related to its functionality and active cis-regulatory elements typically exist within open chromatin regions depleted in nucleosomes (Heintzman et al. 2007; Boyle et al. 2008). These domains can be identified using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) that allows for enrichment of nucleosome-depleted genomic regions when cross-linked chromatin is subjected to phenol-chloroform extraction (Nagy et al. 2003; Hogan et al. 2006) Here, chromatin structure was analyzed in MCF7 and LNCaP cells using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) (Nagy et al. 2003; Hogan et al. 2006) Keywords: FAIRE-chip MCF7 and LNCaP cells were grown in full media, cross-linked and processed as in (Nagy et al. 2003; Hoga

ORGANISM(S): Homo sapiens

SUBMITTER: Jérôme Eeckhoute 

PROVIDER: E-GEOD-11579 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress