Genotyping of human premalignant oral keratinocyte line SVpgC2a loss of heterozygosity (LOH) during FOXM1B-induced malignant transformation

ABSTRACT: Genome-wide SNP profilling for loss of heterozygosity (LOH) during FOXM1B-induced malignant transformation in a human premalignant oral keratinocyte line SVpgC2a. Experiment Overall Design: Eight FOXM1B-induced malignant clones (SVFN1-8) that grew in soft agar were grown as individual cell lines and gDNA harvested from each clone for SNP array analysis compared to wild-type non-transformed SVpgC2a as control to obtain loss of heterozygosity profiles.

ORGANISM(S): Homo sapiens

SUBMITTER: Dr Muy-Teck Teh 

PROVIDER: E-GEOD-11782 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress