Transcription profiling by array of bladder tissue of patients with interstitial cystitis

ABSTRACT: Interstitial cystitis (IC) is a progressive chronic bladder disease with an increasing incidence. Today, IC is diagnosed by subjective symptoms in combination with cystoscopic and histologic evidence. The ultimate goal is the development of a diagnostic assay for IC on a molecular level. A comparative gene expression profile of bladder biopsies from patients with IC and control patients identified candidate marker genes for IC. Experiment Overall Design: Five IC patients and six control patients ('healthy') have been selected for the study. All IC patients had Hunner's ulcers and, with the exception of one person, also glomerulations, whereas the control group did not show these cystoscopic findings. From each IC patient two biopsies have been taken, one from an ulcerated area of the bladd

ORGANISM(S): Homo sapiens

SUBMITTER: Hubert Rehrauer 

PROVIDER: E-GEOD-11783 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress