Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant

ABSTRACT: Growth of isogenic parent ('tdk strain'), 5xECF-sigma factor mutant and complemented mutant strain in the cecum of NMRI inbred mice fed a glycan-restricted, 'simple sugar' diet (35% each glucose and sucrose). Bacteria were collected from mouse distal gut 10 days after colonization. Experiment performed in biological triplicate; for purposes of cross-comparison, profiles were referenced to an in vitro minimal medium glucose chemostat culture (800ml volume, mid-log phase). Reference samples are GSM301635, 301637 and 301639 and are part of series GSE11944.

ORGANISM(S): Bacteroides thetaiotaomicron

SUBMITTER: Eric Martens 

PROVIDER: E-GEOD-11953 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont.

Martens Eric C EC   Chiang Herbert C HC   Gordon Jeffrey I JI  

Cell host & microbe 20081101 5

The distal human gut is a microbial bioreactor that digests complex carbohydrates. The strategies evolved by gut microbes to sense and process diverse glycans have important implications for the assembly and operation of this ecosystem. The human gut-derived bacterium Bacteroides thetaiotaomicron forages on both host and dietary glycans. Its ability to target these substrates resides in 88 polysaccharide utilization loci (PULs), encompassing 18% of its genome. Whole genome transcriptional profil  ...[more]

Similar Datasets

Unknown Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont: ECF mutant
2008-11-21 | GSE11953 | GEO
Transcriptomics Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont
2008-11-20 | E-GEOD-11944 | biostudies-arrayexpress
Unknown Mucosal Glycan Foraging Enhances the Fitness and Transmission of a Saccharolytic Human Distal Gut Symbiont
2008-11-21 | GSE11944 | GEO
Unknown Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont.
| S-EPMC2605320 | biostudies-literature
Transcriptomics Growth of B. thetaiotaomicron on purified host mucosal glycans and glycan fragments
2008-11-20 | E-GEOD-11962 | biostudies-arrayexpress
Transcriptomics Coordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont
2010-05-18 | E-GEOD-14592 | biostudies-arrayexpress
Transcriptomics Glycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron
2008-11-20 | E-GEOD-11980 | biostudies-arrayexpress
Unknown Intrasperm vertical symbiont transmission.
| S-EPMC4034255 | biostudies-other
Unknown In vitro and in vivo transcriptional profiling of Bacteroides thetaiotaomicron
2005-03-30 | GSE2231 | GEO
Unknown Glycan effect on Saccharolytic Human Distal Gut Symbiont, B. thetaiotaomicron
2008-11-21 | GSE11980 | GEO