Inherent gene signature of stage II and III colorectal cancer leads in individual recurrence

ABSTRACT: Background & Aims. The current staging system for colorectal cancer (CRC) based on TNM classification allows prediction of potential recurrence. However, it does not necessarily make reliable personalized prediction of prognosis. In this paper we describe combination of clinicopathological data and gene signature of dissected tumor specimen with stage II and III CRC patients would improve the situation.. Methods. A total of 1978 CRC were collected over 5 years, and then 371 stage II and 322 stage III of them with more than 45.9 months records were subjected to clinicopathological feature analyses. Out of this collection, 129 stage II and III CRC cases were selected for analyses of gene expression profiles with resected specimen. The gene signatures were analyzed by repeated random div

ORGANISM(S): Homo sapiens

SUBMITTER: masakazu miyake 

PROVIDER: E-GEOD-12032 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress