Human embryonic stem cells, differerentiated EBs and adult cells
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Francesco Marincola
PROVIDER: E-GEOD-12250 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells.
Ren Jiaqiang J Jin Ping P Wang Ena E Marincola Francesco M FM Stroncek David F DF
Journal of translational medicine 20090323
<h4>Background</h4>The unique features of human embryonic stem (hES) cells make them the best candidate resource for both cell replacement therapy and development research. However, the molecular mechanisms responsible for the simultaneous maintenance of their self-renewal properties and undifferentiated state remain unclear. Non-coding microRNAs (miRNA) which regulate mRNA cleavage and inhibit encoded protein translation exhibit temporal or tissue-specific expression patterns and they play an i ...[more]
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