Transcripts regulated by elevated DKF-2 (WT background)

ABSTRACT: Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 genes that protect against pathogenic bacteria. Keywords: Induced imune response Three independent biological replicates were isolated for each strain. The strains for each replicate were grown and harvested in parallel.

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Charles Rubin 

PROVIDER: E-GEOD-12456 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress