Transcription profiling of human wild type or domain swap mutants of A-Myb and c-Myb transcription factors in MCF-7 cells or pimary lung epithelial cells or fibroblasts Myb specificity determinants

ABSTRACT: Recombinant adenovirus vectors were used to express wild type or domain swap mutants of A-Myb and c-Myb transcription factors in MCF-7 cells or pimary lung epithelial cells or fibroblasts. The results show that Myb proteins have extreme context specificity and identify sub-domains responsible for the activation of specific sets of target genes.

ORGANISM(S): Homo sapiens

SUBMITTER: Scott Ness 

PROVIDER: E-GEOD-1318 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress