Comparison of relative transcript and protein abundance in Plasmodium falciparum schizont stage parasites

ABSTRACT: Background: Malaria is a one of the most important infectious diseases and is caused by parasitic protozoa of the genus Plasmodium. Previously, the quantitative characterization of the P. falciparum transcriptome demonstrated that the strictly controlled progression of these parasites through their intra-erythrocytic developmental cycle is accompanied by a continuous cascade of gene expression. Although such analyses have proven immensely useful, the precise correlations between transcript and protein abundance remain under-scrutinized. Results: Here, we present a quantitative time-course analysis of relative protein abundance for schizont-stage parasites (34-46 hours post-invasion) based on 2D-gel electrophoresis of protein samples labeled with DIGE fluorescent dyes. For this purpose we

ORGANISM(S): Plasmodium falciparum

SUBMITTER: Neng Zhang 

PROVIDER: E-GEOD-13251 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress