Transcription profiling of human A549 and Calu-6 lung cancer reveals tobacco smoke induces Polycomb-mediated repression of Dickkopf-1 in lung cancer cells

ABSTRACT: Polycomb-mediated repression of Dkk-1 activates Wnt signaling and enhances tumorigenic potential of lung cancer cells following tobacco smoke exposure Experiment Overall Design: microarray techniques were used to examine proliferation and gene expression in A549 and Calu-6 lung cancer cells cultured in normal media with or without tobacco smoke condensate (TSC)

ORGANISM(S): Homo sapiens

SUBMITTER: maocheng yang 

PROVIDER: E-GEOD-13309 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress