Transcription profiling of zebrafish pineal gland and brain tissue from embryonic and adult fish

ABSTRACT: The zebrafish pineal gland (epiphysis) is an autonomous clock organ. In addition to being a site of melatonin production, it contains photoreceptor cells and functions as a circadian clock pace maker, making zebrafish a useful model system to study the developmental control of expression of genes associated with melatonin synthesis and photodetection, and the circadian clock. Here we have used DNA microarray technology to study the zebrafish pineal transcriptome. Analysis of gene expression at five different developmental stages (three embryonic and two adult) has revealed a highly dynamic transcriptional profile, revealing many genes that are highly expressed in the pineal gland. Statistical analysis of the data based on Gene Ontology (GO) annotation indicates that many transcription f

ORGANISM(S): Danio rerio

SUBMITTER: Reiko Toyama 

PROVIDER: E-GEOD-13371 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress