Transcription profiling of mouse liver and brown adipose tissue from KRAP deficient mice

ABSTRACT: KRAP (Ki-ras-induced actin-interacting protein) is a cytoskeleton-associated protein and a ubiquitous protein among tissues, originally identified as a cancer-related molecule. KRAP-deficient (KRAP-/-) mice show enhanced metabolic rate, decreased adiposity, improved glucose tolerance, hypoinsulinemia and hypoleptinemia. KRAP-/- mice are also protected against high-fat diet-induced obesity and insulin resistance despite of hyperphagia. This SuperSeries is composed of the following subset Series:; GSE13582: Expression data from BAT of the KRAP deficient mice; GSE13583: Expression data from liver of the KRAP deficient mice Experiment Overall Design: Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: takahiro fujimoto 

PROVIDER: E-GEOD-13585 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress