Analyses of cyclin D1 function using a "genetic-proteomic" approach

ABSTRACT: We examined the transcriptional function of cyclin D1 in mouse development using two approaches. First, we queried association of cyclin D1 with the genome of E14.5 mouse embryos using ChIP-on-chip approach. We observed binding of cyclin D1 to several promoter regions. Second, we compared gene expression profiles between wild-type and cyclin D1-null retinas. We observed several transcripts with altered levels in cyclin D1-null organs. Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Frederic Bienvenu 

PROVIDER: E-GEOD-13636 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress